“Also related to the magic of language mysticism is the author’s view that the six dimensions of heaven are “sealed” (1:13) by the six permutations of “His great name Yaho” (Hebrew YHW). These three consonants, utilized in Hebrew as matres lectionis for the vowels i, a, and o, which are not written, make up the divine name Yaho, which contains the three consonants of the four-letter name of God, YHWH, as well as the form Yao, which penetrated into the documents of Hellenistic syncretism where its permutations likewise play a role. The signs that were subsequently developed to designate vowels were still unknown to the author.
This idea concerning the function of the name Yaho or Yao suggests important parallels. In the system of the Gnostic Valentinus, Iao is the secret name with which the Horos (literally: the limit, the limitation!) frightens away from the world of the pleroma the Sophia-Akhamoth who is in pursuit of Christ.
Does not the cosmos (as distinct from the pleroma), sealed by means of the six permutations of Yao in the Book Yesirah, constitute a sort of monotheistic parallel, perhaps even inspired by polemical intentions, to this Valentinian myth? In another text of a manifestly Jewish-syncretistic character, we similarly find the name Iao, as an invocation that consolidates the world in its limits, a perfect analogy to the sealing in Yesirah: in the cosmogony of the Leiden magical papyrus the earth writhed when the Pythian serpent appeared “and reared up powerfully. But the pole of heaven remained firm, even though it risked being struck by her. Then the god spoke: Iao! And everything was established and a great god appeared, the greatest, who arranged that which was formerly in the world and that which will be, and nothing in the realm of the Height was without order any more.”
The name Iao appears again among the secret names of this greatest god himself. It is difficult not to suspect a relation here between Jewish conceptions and those of Gnosticism and syncretism. This “sealing” of the Creation by means of the divine name belongs to the old stock of ideas of the Merkabah gnosis; it is attested in chapter 9 of the “Greater Hekhaloth.” What is said in the “Book of Creation” of the “six directions” of space is here said of the “orders of the Creation,” therefore, of the cosmos in general, whose preservation within its established arrangements, sidre bereshith, is due to its “sealing” by the great name of God.”
–Gershom Scholem, Origins of the Kabbalah, 1987, pp. 31-3.